Combined effect of cyclophosphamide and extracts of Crotalaria and Senecio plants on experimental tumours.

Combined Effect of Ginger and Pumpkin Seed Extracts on Rat Testis and Serum Biochemical Parameters after Cyclophosphamide Treatment

Introduction: Cyclophosphamide is a chemotherapy drug with several side effects on various organs such as male reproductive system that can cause infertility. In this study, we assessed combined effect of ginger and pumpkin extractson rat testis after CP injection. Methods: Forty adult male rats were randomly divided into 4 groups: The control group received intraperitoneal injection of ...

General Remarks on the Substances Considered

This volume of the IARC Monographs considers some traditional herbal medicines, including extracts from certain plants of the genera Aristolochia, Rubia, Morinda and Senecio; some mycotoxins, specifically aflatoxins and fumonisin B1; and two industrial chemicals, naphthalene and styrene. Of these, the Monographs have previously evaluated several of the pyrrolizidine alkaloids that occur in cert...

Pyrrolizidine Alkaloid– Containing Toxic Plants (<i>Senecio, Crotalaria, Cynoglossum, Amsinckia, Heliotropium, </i> and <i>Echium</i> spp.)

Qualitative and Quantitative Determination of Pyrrolizidine Alkaloids of Wheat and Flour Contaminated with Senecio in Mazandaran Province Farms

The Pyrrolizidine Alkaloids (PAs) are a group of chemicals found in a variety of plant species throughout the world. These toxic alkaloids are distributed mainly in Senecio (Compositae), Crotalaria (Legominosae) and Heliotropium (Boraginaceae) species. Plants containing these alkaloids cause significant mammalian morbidity and mortality, especially in humans. Upon ingestion, metabolic activatio...

تأثیر شیرابه میوه گیاه خرمندی بر میزان گلوتاتیون کبدی در حیوانات مواجه یافته با عصاره آلکالوئیدی گیاه پیرگیاه

Background and purpose: Glutathione is one of the main antioxidants in animals which can protect against hazardous oxidative substances. Diospyros lotus consisted of antioxidants such as flavonoids and naphthoguinones which can influence the glutathione levels. On the other hand, Senecio vulgaris is expected to change the glutathione level, because of possessing toxic and oxidative compounds ca...